The Future of Noninvasive Medical Devices: Purdue University Researchers Developing Innovative Technology to Monitor and Treat Physiological and Psyc
Key Highlights :
Innovative medical technologies are being developed at Purdue University's College of Engineering that could revolutionize the way we monitor and treat certain physiological and psychological conditions. Led by Wenzhuo Wu, the Ravi and Eleanor Talwar Rising Star Associate Professor of Industrial Engineering, the research team has developed a noninvasive, wearable sensor called EPICS that monitors uric acid (UA) levels in human sweat. This technology could provide unprecedented diagnosis, therapy, and prognosis of conditions such as anxiety and hypertension.
Uric acid is a byproduct of purine metabolism in the human body and is known to trigger inflammation as an immune response. Abnormal levels of UA have been linked to various physiological diseases, such as gout, hyperuricemia, and hypertension, as well as psychological conditions, such as anxiety and depression. These conditions are estimated to affect 1-4% of the world's population and cost upwards of $20 billion in medical expenses each year.
Currently, the most common method for monitoring UA levels is through blood samples. However, this process is intrusive and results can be delayed, making it difficult to provide timely and precise treatment. To address this issue, Wu and his team have developed EPICS, which are flexible and noninvasive sensors that monitor UA levels in human sweat. These sensors are made from zinc oxide, a nontoxic, biocompatible, and electrochemically active material.
The EPICS devices have been tested at Purdue University's Flex Lab and have shown to be four times more sensitive than traditional UA sensors. Additionally, they are able to detect UA levels in human sweat with a higher limit of detection than other sensors. This technology also has the potential to be powered by mechanical energy, such as that from the human body, making it even more efficient.
Wu and the research team are now conducting additional testing to validate the on-body sensing of EPICS and to evaluate the sensor's performance over time. If successful, this technology could drastically improve the diagnosis, therapy, and prognosis of various physiological and psychological conditions. It could also reduce the cost of medical expenses associated with these conditions, making treatment more accessible to those who need it.
This research has been published in Nano Energy and is a testament to the dedication and ingenuity of the Purdue University research team. As the technology continues to be tested and refined, it is sure to make a lasting impact on the medical industry.
